Article
Helicobacter pylori vacA Genotypes in Chronic Gastritis and Gastric Carcinoma Patients from Macau, China.
Toxins - 5 May 2016
Pinto-Ribeiro Ines, Ferreira Rui M, Batalha Sellma, Hlaing Thazin, Wong Sio In, Carneiro Fatima, Figueiredo Ceu
Abstract excerpt
Helicobacter pylori is the major triggering factor for gastric carcinoma, but only a small proportion of infected patients develop this disease. Differences in virulence observed among H. pylori strains, namely in the vacuolating cytotoxin vacA gene, may contribute to this discrepancy. Infection with vacA s1, i1 and m1 strains increases the risk for progression of gastric premalignant lesions and for gastric...
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