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Article

VacA and CagA Status as Biomarker of Two Opposite End Outcomes of Helicobacter pylori Infection (Gastric Cancer and Duodenal Ulcer) in a Moroccan Population.

PloS one - 1 Jan 2017

El Khadir Mounia, Alaoui Boukhris Samia, Benajah Dafr-Allah, El Rhazi Karima, Ibrahimi Sidi Adil, El Abkari Mohamed, Harmouch Taoufiq, Nejjari Chakib, Mahmoud Mustapha, Benlemlih Mohamed, Bennani Bahia

Abstract excerpt

Helicobacter pylori (H. pylori) infection induces inflammation of the gastric mucosa, which may progress to precancerous lesions leading to gastric cancer. Pathological determinism is associated to some virulence genes of the bacterium, notably the vacA and cagA genes. The present study aimed to determine the H. pylori genotypes distribution and their association with sex, age and gastric diseases in a Moroccan...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28125638
DOI: 10.1371/journal.pone.0170616
PMCID: PMC5268467

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