Article
The Role of fadD19 and echA19 in Sterol Side Chain Degradation by Mycobacterium smegmatis.
Molecules (Basel, Switzerland) - 6 May 2016
Wrońska Natalia, Brzostek Anna, Szewczyk Rafał, Soboń Adrian, Dziadek Jarosław, Lisowska Katarzyna
Abstract excerpt
Mycobacteria are able to degrade natural sterols and use them as a source of carbon and energy. Several genes which play an important role in cholesterol ring degradation have been described in Mycobacterium smegmatis. However, there are limited data describing the molecular mechanism of the aliphatic side chain degradation by Mycobacterium spp. In this paper, we analyzed the role of the echA19 and fadD19 genes...
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