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Article

ChoD and HsdD can be dispensable for cholesterol degradation in mycobacteria.

The Journal of steroid biochemistry and molecular biology - 1 Mar 2013

Brzostek Anna, Rumijowska-Galewicz Anna, Dziadek Bozena, Wojcik Ewelina A, Dziadek Jaroslaw

Abstract excerpt

Cholesterol degradation is achieved through a complex metabolic pathway that starts with the oxidation of the 17-alkyl side chain and the steroid ring system. In bacteria, the oxidation of the 3β-hydroxyl group and isomerization of the resulting cholest-5-en-3-one to cholest-4-en-3-one is catalyzed by hydroxysteroid dehydrogenase (HsdD) or cholesterol oxidase (ChoD). Genes encoding both enzymes were annotated in...

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Identifiers

PMID: 23064392
DOI: 10.1016/j.jsbmb.2012.09.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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