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Article

Targeted Sequencing and Meta-Analysis of Preterm Birth.

PloS one - 1 Jan 2016

Uzun Alper, Schuster Jessica, McGonnigal Bethany, Schorl Christoph, Dewan Andrew, Padbury James

Abstract excerpt

Understanding the genetic contribution(s) to the risk of preterm birth may lead to the development of interventions for treatment, prediction and prevention. Twin studies suggest heritability of preterm birth is 36-40%. Large epidemiological analyses support a primary maternal origin for recurrence of preterm birth, with little effect of paternal or fetal genetic factors. We exploited an "extreme phenotype" of...

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Source

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Identifiers

PMID: 27163930
DOI: 10.1371/journal.pone.0155021
PMCID: PMC4862658

Genes

AKT3
ATM
AZU1
IGF1
IQGAP2
RAF1
SERPINB8
SOS1
WASF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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