Article

Genetic and epigenetic mechanisms of preterm birth: Advancing from multi-omics insights to precision prevention and clinical management

2026-05-27

Abstract excerpt

<b>1. </b>Preterm birth (PTB) is the leading cause of neonatal mortality and neurodevelopmental impairments worldwide. Its pathogenesis arises from the complex interplay among genetic susceptibility, environmental exposures, and epigenetic regulation. The maternal genome plays a predominant role in shaping PTB risk, modulating the timing of delivery through the regulation of inflammatory pathways, uterine contract...

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Literature Corpus work: 80dc0377-42fb-50ed-abff-2fc9208f3ca4
DOI: 10.22541/authorea.15003735/v1

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