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Article

A Novel Small Molecule Modulator of Amyloid Pathology.

Journal of Alzheimer's disease : JAD - 4 May 2016

Lovell Mark A, Lynn Bert C, Fister Shuling, Bradley-Whitman Melissa, Murphy M Paul, Beckett Tina L, Norris Christopher M

Abstract excerpt

Because traditional approaches to drug development for Alzheimer's disease are becoming increasingly expensive and in many cases disappointingly unsuccessful, alternative approaches are required to shift the paradigm. Following leads from investigations of dihydropyridine calcium channel blockers, we observed unique properties from a class of functionalized naphthyridines and sought to develop these as novel...

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Identifiers

PMID: 27163808
DOI: 10.3233/JAD-151160
PMCID: PMC6025774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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