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Article

Role of HIF1A, VEGFA and VEGFR2 SNPs in the Susceptibility and Progression of COPD in a Spanish Population.

PloS one - 1 Jan 2016

Baz-Dávila Rebeca, Espinoza-Jiménez Adriana, Rodríguez-Pérez María Del Cristo, Zulueta Javier, Varo Nerea, Montejo Ángela, Almeida-González Delia, Aguirre-Jaime Armando, Córdoba-Lanús Elizabeth, Casanova Ciro

Abstract excerpt

Hypoxia is involved in the development of chronic inflammatory processes. Under hypoxic conditions HIF1A, VEGF and VEGFR2 are expressed and mediate the course of the resultant disease. The aim of the present study was to define the associations between tSNPs in these genes and COPD susceptibility and progression in a Spanish cohort. The T alleles in rs3025020 and rs833070 SNPs (VEGFA gene) were less frequent in...

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Source

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Identifiers

PMID: 27163696
DOI: 10.1371/journal.pone.0154998
PMCID: PMC4862690

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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