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Targeting survivin as a potential new treatment for chondrosarcoma of bone

9 May 2016

Abstract excerpt

Chondrosarcomas are malignant cartilage-forming bone tumors, which are intrinsically resistant to chemo- and radiotherapy, leaving surgical removal as the only curative treatment option. Therefore, our aim was to identify genes involved in chondrosarcoma cell survival that could serve as a target for therapy. siRNA screening for 51 apoptosis-related genes in JJ012 chondrosarcoma cells identified BIRC5, encoding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27159675
DOI: 10.1038/oncsis.2016.33

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