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Article

BIRC5 expression is a poor prognostic marker in Ewing sarcoma

7 Sept 2012

Abstract excerpt

BACKGROUND: BIRC5 (Survivin), an inhibitor of apoptosis protein (IAP), is over-expressed in several human cancers and increased expression is associated with poor prognosis. The goal of the current study was to evaluate the role of BIRC5 in Ewing sarcoma (ES), the second most common pediatric bone sarcoma. PROCEDURE: BIRC5 protein expression was determined in ES cell lines using Western Blot analysis. Functional...

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Identifiers

PMID: 22961763
DOI: 10.1002/pbc.24290

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