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Article

Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.

Cellular & molecular immunology - 1 Feb 2018

Xie Yuanyuan, Wen Huiqin, Yan Ke, Wang Shushu, Wang Xuesong, Chen Jian, Li Yuanling, Xu Yuanhong, Zhong Zhengrong, Shen Jilong, Chu Deyong

Abstract excerpt

Recent studies indicated that type II Toxoplasma gondii (Tg) GRA15II favored the generation of classically activated macrophages (M1), whereas type I/III TgROP16I/III promoted the polarization of alternatively activated macrophages (M2). A number of studies have demonstrated that M2 cells are involved in the pathogenesis of the liver fibrogenesis caused by Schistosoma japonicum. The purpose of the present study...

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Identifiers

PMID: 27157496
DOI: 10.1038/cmi.2016.21
PMCID: PMC5811674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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