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Article

Toxoplasma Chinese 1 Strain of WH3Δrop16I/III /gra15II Genetic Background Contributes to Abnormal Pregnant Outcomes in Murine Model.

Frontiers in immunology - 1 Jan 2018

Wang Cong, Cheng Weisheng, Yu Qian, Xing Tian, Chen Shoubin, Liu Lei, Yu Li, Du Jian, Luo Qingli, Shen Jilong, Xu Yuanhong

Abstract excerpt

Toxoplasma gondii infection evokes a strong Th1-type response with interleukin (IL)-12 and interferon (IFN)-γ secretion. Recent studies suggest that the infection of pregnant mice with T. gondii may lead to adverse pregnancy results caused by subversion of physiological immune tolerance at maternofetal interface rather than direct invasion of the parasite. Genotype-associated dense granule protein GRA15II tends...

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Identifiers

PMID: 29910815
DOI: 10.3389/fimmu.2018.01222
PMCID: PMC5992278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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