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Article

Immunohistochemical assessment of M1/M2 macrophage phenotypes in hepatic hydatid disease.

Acta tropica - 1 Sept 2026

Elhamed Sara Mohamed Abd, Sweed Dina, Sallam Hebatallah, Sabry Shaymaa

Abstract excerpt

INTRODUCTION: Macrophages are key immune defenders in hydatid disease. While M1 macrophages express iNOS and M2 macrophages express TGF-β, the relationship between STAT6 activation and macrophage subsets remains unclear in hydatid disease. MATERIALS AND METHODS: The study included 60 patients with visceral hydatid disease, and cyst specimens were categorized as either fertile or non-fertile hydatid cysts....

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Antigens, CD
Antigens, Differentiation, Myelomonocytic
Immunohistochemistry
Macrophages
Nitric Oxide Synthase Type II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

STAT6 Transcription Factor

Transforming Growth Factor beta

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Identifiers

PMID: 42392482
DOI: 10.1016/j.actatropica.2026.108214

Genes

STAT6
CD68

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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