Article
Genotype-Associated Arginase 1 Expression in Rat Peritoneal Macrophages Induced by Toxoplasma gondii.
The Journal of parasitology - 1 Aug 2015
Zhang Qian, He Liuyuan, Kong Lanting, Zhang Yihua, Chen He, An Ran, Wang Lu, Wang Weiwei, Xu Xiucai, Zhang Aimei, Cai Yihong, Li Min, Wen Huiqin, Luo Qingli, Shen Jilong
Abstract excerpt
Toxoplasma gondii induces polarization of mouse macrophages, including both classically activated macrophages (M1) and alternatively activated macrophages (M2) in a genotype-related manner. Here we present a novel result that the Wh6 strain with type Chinese 1, which is predominantly prevalent in China, induces Arg1 expression in a STAT6-dependent manner in primary rat peritoneal macrophages as compared to the...
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