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IKZF1andCRLF2gene alterations correlate with poor prognosis in JapaneseBCR‐ABL1‐negative high‐risk B‐cell precursor acute lymphoblastic leukemia

27 Jun 2013

Abstract excerpt

BACKGROUND: Genome-wide analysis studies have demonstrated that IKZF1, CRLF2, and JAK2 gene alterations correlate with poor prognosis in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However, the prognostic significance for these gene alterations has not been clarified in Japanese patients. PROCEDURE: A total of 194 patients with BCP-ALL enrolled in the Japanese Children's Cancer & Leukemia...

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PMID: 23804397
DOI: 10.1002/pbc.24571

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