Article
Multiple gene mutations identified in patients infected with influenza A (H7N9) virus.
Scientific reports - 9 May 2016
Chen Cuicui, Wang Mingbang, Zhu Zhaoqin, Qu Jieming, Xi Xiuhong, Tang Xinjun, Lao Xiangda, Seeley Eric, Li Tao, Fan Xiaomei, Du Chunling, Wang Qin, Yang Lin, Hu Yunwen, Bai Chunxue, Zhang Zhiyong, Lu Shuihua, Song Yuanlin, Zhou Wenhao
Abstract excerpt
Influenza A (H7N9) virus induced high mortality since 2013. It is important to elucidate the potential genetic variations that contribute to virus infection susceptibilities. In order to identify genetic mutations that might increase host susceptibility to infection, we performed exon sequencing and validated the SNPS by Sanger sequencing on 18 H7N9 patients. Blood samples were collected from 18 confirmed H7N9...
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