Article
Novel susceptibility loci for A(H7N9) infection identified by next generation sequencing and functional analysis.
Scientific reports - 16 Jul 2020
Zhao Baihui, Chen Yongkun, Li Mo, Zhou Jianfang, Teng Zheng, Chen Jian, Zhao Xue, Wu Hao, Bai Tian, Mao Shenghua, Fang Fanghao, Chu Wei, Huang Hailiang, Huai Cong, Shen Lu, Zhou Wei, Sun Liangdan, Zheng Xiaodong, Cheng Guangxia, Sun Ye, Wang Dayan, He Lin, Shu Yuelong, Zhang Xi, Qin Shengying
Abstract excerpt
The A(H7N9) virus strain that emerged in 2013 was associated with a high fatality rate and may become a long-term threat to public health. A(H7N9) disease incidence is disproportionate to viral exposure, suggesting that host genetic factors may significantly influence susceptibility to A(H7N9) infection. Human genome variation in conferring risk for A(H7N9) infection in Chinese populations was identified by a...
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