Article
Single nucleotide polymorphism-based microarray analysis for the diagnosis of hydatidiform moles.
Molecular medicine reports - 1 Jul 2016
Xie Yingjun, Pei Xiaojuan, Dong Yu, Wu Huiqun, Wu Jianzhu, Shi Huijuan, Zhuang Xuying, Sun Xiaofang, He Jialing
Abstract excerpt
In clinical diagnostics, single nucleotide polymorphism (SNP)-based microarray analysis enables the detection of copy number variations (CNVs), as well as copy number neutral regions, that are absent of heterozygosity throughout the genome. The aim of the present study was to evaluate the effectiveness and sensitivity of SNP‑based microarray analysis in the diagnosis of hydatidiform mole (HM). By using...
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