Article
Precise DNA genotyping diagnosis of hydatidiform mole.
Obstetrics and gynecology - 1 Apr 2010
Lipata Fredilyn, Parkash Vinita, Talmor Monica, Bell Susan, Chen Suping, Maric Vesna, Hui Pei
Abstract excerpt
OBJECTIVE: To estimate whether tissue DNA genotyping is effective for the confirmation and subclassification of hydatidiform moles. METHODS: Consecutive cases of products of conception were selected based on histologic alterations that are suspicious for molar pregnancy. DNA genotyping was performed by a multiplex polymerase chain reaction targeting 15 tetrameric polymorphic loci of the human genome. RESULTS: A...
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