Article
Molecular genotyping of hydatidiform moles: analytic validation of a multiplex short tandem repeat assay.
The Journal of molecular diagnostics : JMD - 1 Nov 2009
Murphy Kathleen M, McConnell Thomas G, Hafez Michael J, Vang Russell, Ronnett Brigitte M
Abstract excerpt
Distinction of hydatidiform moles from non-molar (NM) specimens, as well as their subclassification as complete (CHM) versus partial hydatidiform moles (PHM), is important for clinical management and accurate risk assessment for persistent gestational trophoblastic disease. Because diagnosis of hydatidiform moles based solely on morphology suffers from poor interobserver reproducibility, a variety of ancillary...
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