Article
Genotypic analysis of hydatidiform mole: an accurate and practical method of diagnosis.
The American journal of surgical pathology - 1 Mar 2008
Bifulco Carlo, Johnson Chaline, Hao Liming, Kermalli Husnain, Bell Susan, Hui Pei
Abstract excerpt
Molar gestations are defined at the genetic level by their unique parental chromosomal compositions. Their diagnosis, however, currently relies largely on histologic features and on the occasional support of ancillary immunohistochemical and DNA ploidy analyses. We sought to validate DNA genotyping for the routine diagnosis and subtyping of hydatidiform moles (HMs) by analyzing 52 cases of molar pregnancy and...
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