p16/Ki-67 dual-stained cytology for detecting cervical (pre)cancer in a HPV-positive gynecologic outpatient population.

doi:10.1038/modpathol.2016.80

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Article

p16/Ki-67 dual-stained cytology for detecting cervical (pre)cancer in a HPV-positive gynecologic outpatient population.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2016

Luttmer Roosmarijn, Dijkstra Maaike G, Snijders Peter J F, Berkhof Johannes, van Kemenade Folkert J, Rozendaal Lawrence, Helmerhorst Theo J M, Verheijen René H M, Ter Harmsel W Abraham, van Baal W Marchien, Graziosi Peppino G C M, Quint Wim G V, Spruijt Johan W M, van Dijken Dorenda K E, Heideman Daniëlle A M, Meijer Chris J L M

Abstract excerpt

Women who test positive for a high-risk type of the human papillomavirus (HPV) require triage testing to identify those women with cervical intraepithelial neoplasia grade 3 or cancer (≥CIN3). Although Pap cytology is considered an attractive triage test, its applicability is hampered by its subjective nature. This study prospectively compared the clinical performance of p16/Ki-67 dual-stained cytology to that of...

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PMID: 27150161
DOI: 10.1038/modpathol.2016.80

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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