Article
p16/Ki-67 dual staining in cervico-vaginal cytology: correlation with histology, Human Papillomavirus detection and genotyping in women undergoing colposcopy.
Gynecologic oncology - 1 Aug 2012
Donà Maria Gabriella, Vocaturo Amina, Giuliani Massimo, Ronchetti Livia, Rollo Francesca, Pescarmona Edoardo, Carosi Mariantonia, Vocaturo Giuseppe, Benevolo Maria
Abstract excerpt
OBJECTIVES: To evaluate the CINtec PLUS assay (mtm laboratories), a new immunocytochemical method for the simultaneous detection of p16(INK4a) and Ki-67, in liquid-based cervico-vaginal cytology, investigating the association of the dual staining with HPV infection and genotyping as well as cytological and histological abnormalities. METHODS: 140 women with a cervico-vaginal sample obtained immediately before the...
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