Article
Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2016
Ritterhouse Lauren L, Nowak Jonathan A, Strickland Kyle C, Garcia Elizabeth P, Jia Yonghui, Lindeman Neal I, Macconaill Laura E, Konstantinopoulos Panagiotis A, Matulonis Ursula A, Liu Joyce, Berkowitz Ross S, Nucci Marisa R, Crum Christopher P, Sholl Lynette M, Howitt Brooke E
Abstract excerpt
Extrauterine high-grade serous carcinomas can exhibit various histologic patterns including (1) classic architecture that is papillary, micropapillary and infiltrative and (2) solid, endometrioid, and transitional (ie, SET) patterns. Although the SET pattern has been associated with germline BRCA mutations, potential molecular underpinnings have not been fully investigated. DNA was isolated from 174 carcinomas of...
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