Article
The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: A systematic review.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jul 2016
Muka T, Nano J, Voortman T, Braun K V E, Ligthart S, Stranges S, Bramer W M, Troup J, Chowdhury R, Dehghan A, Franco O H
Abstract excerpt
BACKGROUND: New evidence suggests the potential involvement of epigenetic mechanisms in type 2 diabetes (T2D) as a crucial interface between the effects of genetic predisposition and environmental influences. AIM: To systematically review studies investigating the association between epigenetic marks (DNA methylation and histone modifications) with T2D and glycemic traits (glucose and insulin levels, insulin...
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