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Article

Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer.

International journal of oncology - 1 Dec 2020

Oh Sangphil, Song Hoogeun, Freeman Willard M, Shin Sook, Janknecht Ralf

Abstract excerpt

ETS variant 1 (ETV1) is an oncogenic transcription factor. However, its role in colorectal cancer has remained understudied. The present study demonstrated that ETV1 downregulation led to reduced HCT116 colorectal cancer cell growth and clonogenic activity. Furthermore, the ETV1 mRNA levels were enhanced in colorectal tumors and were associated with disease severity. In addition, ETV1 directly bound to Jumonji C...

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Source

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Identifiers

PMID: 33174020
DOI: 10.3892/ijo.2020.5133
PMCID: PMC7646594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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