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Evaluation of common genetic variants in vitamin E-related pathway genes and colorectal cancer susceptibility.

Archives of toxicology - 1 Jul 2021

Zhang Qiuyi, Meng Yixuan, Du Mulong, Li Shuwei, Xin Junyi, Ben Shuai, Zhang Zhengdong, Gu Dongying, Wang Meilin

Abstract excerpt

Vitamin E is effective for preventing the risk of cancer. However, few studies have elucidated the mechanism of vitamin E in cancer occurrence. Herein, we aimed to identify the genetic variants in vitamin E-related pathway genes associated with colorectal cancer risk. We applied logistic regression models to assess the association between single-nucleotide polymorphisms (SNPs) in vitamin E-related pathway genes...

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Case-Control Studies
Colorectal Neoplasms
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide
Transcriptional Elongation Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34009442
DOI: 10.1007/s00204-021-03078-0

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