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Article

MMP-3 gene polymorphisms and Osteosarcoma.

Indian journal of experimental biology - 1 Mar 2016

Adiguzel Mustafa, Horozoglu Cem, Kilicoglu Onder, Ozger Harzem, Acar Leyla, Ergen Arzu

Abstract excerpt

Osteosarcoma (OSA) is the most common adolescence cancer among all primary bone tumors next only to multiplemyeloma. It has a substantially worse prognosis and ability to metastasize to lung. MMPs (matrix metalloproteinases) are among the major proteases that take part in regulation of ECM (extracellular matrix). MMPs play an active role in the formation of the osteoid tissue, rich in collagens and other ECM...

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PMID: 27145630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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