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Risk factor of elevated matrix metalloproteinase-3 gene expression in synovial fluid in knee osteoarthritis women

31 Mar 2023

Abstract excerpt

INTRODUCTION: Metalloproteinases-3 (MMP3) are the main enzymes involved in cartilage degradation. Several genetic and non-genetic factors can increase the expression of MMP3 in patients with osteoarthritis (OA). This study aims to analyze the risk factors associated with the expression of the MMP3 gene rs679620 fluid synovial knee OA patients. METHODS: A cross-sectional study was conducted at the orthopedic...

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PMID: 37000824
DOI: 10.1371/journal.pone.0283831

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