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Article

Effect of TIMP2/TIMP3 genes on the risk of osteosarcoma in Zhejiang population.

Medicine - 19 Mar 2021

Wu Zhongwei, Chen Huali, Pan Liwei, Yu Weiyang, Lou Chao, Chen Jian, He Dengwei

Abstract excerpt

ABSTRACT: Osteosarcoma is a malignant tumor that develops from a mesenchymal cell line and is caused by gene-environment interactions. This study aimed to explore whether TIMP2/TIMP3 polymorphisms influenced the osteosarcoma risk.The expression of the TIMP2 and TIMP3 genes in osteosarcoma histiocytes was analyzed by immunohistochemistry. In this case-control study, which includes samples from 499 patients and 500...

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Identifiers

PMID: 33725949
DOI: 10.1097/MD.0000000000024818
PMCID: PMC7982212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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