Genetic polymorphisms in MMP 2, 3 and 9 genes and the susceptibility of osteosarcoma in a Chinese Han population.

doi:10.3109/1354750X.2015.1118550

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Article

Genetic polymorphisms in MMP 2, 3 and 9 genes and the susceptibility of osteosarcoma in a Chinese Han population.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2016

Cui Yan, Zhu Jia-Jun, Ma Cheng-Bin, Cui Kai, Wang Feng, Ni Sheng-Hui, Zhang Zhi-Yu

Abstract excerpt

BACKGROUND: There are no data about the role of MMPs polymorphism in development of osteosarcoma. PATIENTS AND METHODS: Two-hundred fifty-one patients with osteosarcoma and 251 healthy controls were included to investigate the association between the MMP2, 3, 9 polymorphisms and the risk of osteosarcoma. RESULTS: Compared with the MMP2 SNP rs243865 homozygote CC, The heterozygous CT genotype was associated with...

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PMID: 26754027
DOI: 10.3109/1354750X.2015.1118550

Genes

MMP2
MMP3
MMP9

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