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Article

Collecting duct carcinoma of the kidney is associated with CDKN2A deletion and SLC family gene up-regulation.

Oncotarget - 24 May 2016

Wang Jianmin, Papanicolau-Sengos Antonios, Chintala Sreenivasulu, Wei Lei, Liu Biao, Hu Qiang, Miles Kiersten Marie, Conroy Jeffrey M, Glenn Sean T, Costantini Manuela, Magi-Galluzzi Cristina, Signoretti Sabina, Choueiri Toni, Gallucci Michele, Sentinelli Steno, Fazio Vito M, Poeta Maria Luana, Liu Song, Morrison Carl, Pili Roberto

Abstract excerpt

The genetic landscape and molecular features of collecting duct carcinoma (CDC) of the kidney remain largely unknown. Herein, we performed whole exome sequencing (WES) and transcriptome sequencing (RNASeq) on 7 CDC samples (CDC1 -7). Among the 7 samples, 4 samples with matched non-tumor tissue were used for copy number analysis by SNP array data. No recurrent somatic SNVs were observed except for MLL, which was...

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Share to Carcinoma, Renal Cell
Share to Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

Share to In Situ Hybridization, Fluorescence

Share to Kidney

Share to Kidney Neoplasms

Share to Myeloid-Lymphoid Leukemia Protein

Share to Sequence Analysis, RNA

Source

Open in PubMed Open full text

Identifiers

PMID: 27144525
DOI: 10.18632/oncotarget.9093
PMCID: PMC5058651

Genes

ATM
CBFB
CREBBP
IKZF1
KDR
KRAS
NACA
NUP98
PRDM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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