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Familial early-onset dementia with complex neuropathologic phenotype and genomic background.

Neurobiology of aging - 1 Jun 2016

Alexander John, Kalev Ognian, Mehrabian Shima, Traykov Latchezar, Raycheva Margariata, Kanakis Dimitrios, Drineas Petros, Lutz Mirjam I, Ströbel Thomas, Penz Thomas, Schuster Michael, Bock Christoph, Ferrer Isidro, Paschou Peristera, Kovacs Gabor G

Abstract excerpt

Despite significant progress in our understanding of hereditary neurodegenerative diseases, the list of genes associated with early-onset dementia is not yet complete. In the present study, we describe a familial neurodegenerative disorder characterized clinically as the behavioral and/or dysexecutive variant of Alzheimer's disease with neuroradiologic features of Alzheimer's disease, however, lacking amyloid-β...

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PMID: 27143436
DOI: 10.1016/j.neurobiolaging.2016.03.012

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DDI1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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