Article

Genome sequencing for early-onset dementia: high diagnostic yield and frequent observation of multiple contributory alleles

2019-08-28

Abstract excerpt

<h4>ABSTRACT</h4> We assessed the utility of genome sequencing for early-onset dementia. Participants were selected from a memory disorders clinic. Genome sequencing was performed along with C9orf72 repeat expansion testing. All returned sequencing results were Sanger validated clinically. Prior clinical diagnoses included Alzheimer’s disease, frontotemporal dementia, and unspecified dementia. The mean age-of-on...

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Literature Corpus work: 8bae2d03-347e-539c-a403-60dd5e9558c4
DOI: 10.1101/748046

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