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Article

Function and Inhibitory Mechanisms of Multidrug Efflux Pumps

3 Dec 2021

Abstract excerpt

Multidrug efflux pumps are inner membrane transporters that export multiple antibiotics from the inside to the outside of bacterial cells, contributing to bacterial multidrug resistance (MDR). Postgenomic analysis has demonstrated that numerous multidrug efflux pumps exist in bacteria. Also, the co-crystal structural analysis of multidrug efflux pumps revealed the drug recognition and export mechanisms, and the...

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Share to Antibiotic Resistance in Bacteria
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PMID: 34925258
DOI: 10.3389/fmicb.2021.737288

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