Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell transcriptome reveals diversity of Müller cells with different metabolic-mitochondrial signatures in normal and degenerated macula

22 Dec 2022

Abstract excerpt

maintaining environmental homeostasis. In response to injury and/or neuronal degeneration, Müller cells undergo morphological and functional alternations, known as reactive gliosis documented in multiple retinal diseases, including age-related macular degeneration (AMD), retinitis pigmentosa, diabetic retinopathy, and traumatic retinal detachment. But the functional consequences of Müller glia cell reactivation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36620436
DOI: 10.3389/fnins.2022.1079498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell transcriptome reveals diversity of Müller cells with different metabolic-mitochondrial signatures in normal and degenerated maculaPMID 36620436Read ↗

Translatomic response of retinal Müller glia to acute and chronic stressSemantic proximity Read ↗

Interpretable Aging Signatures in Human Retinal Cell Types Revealed by Single-Cell RNA Sequencing and Sparse Logistic RegressionSemantic proximity Read ↗

Single-cell transcriptomic analysis revealing changes in retinal cell subpopulation levels and the pathways involved in diabetic retinopathySemantic proximity Read ↗

Generation of human neural retina transcriptome atlas by single cell RNA sequencingSemantic proximity Read ↗

Sacrificing Adaptability for Functionality: The Ivory Tower of Macular Müller CellsSemantic proximity Read ↗

Single-cell analysis of the human retina reveals stage-linked microglial states and neural-immune circuit rewiring in diabetic retinopathySemantic proximity Read ↗

Pathway-selective mitophagy regulates retinal physiology and neurogenic transitions in Muller gliaSemantic proximity Read ↗

Beyond Genetics: The Role of Metabolism in Photoreceptor Survival, Development and RepairSemantic proximity Read ↗

Single cell RNA sequencing unravels the transcriptional network underlying zebrafish retina regenerationSemantic proximity Read ↗

Integrative single-cell and bulk RNA-seq analysis in human retina identified cell type-specific composition and gene expression changes for age-related macular degenerationSemantic proximity Read ↗

Müller cell metabolic chaos during retinal degeneration.Semantic proximity Read ↗

Retinal aging transcriptome and cellular landscape in association with the progression of age-related macular degenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.