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Article

Screening PCR Versus Sanger Sequencing: Detection of CALR Mutations in Patients With Thrombocytosis.

Annals of laboratory medicine - 1 Jul 2016

Jeong Ji Hun, Lee Hwan Tae, Seo Ja Young, Seo Yiel Hea, Kim Kyung Hee, Kim Moon Jin, Lee Jae Hoon, Park Jinny, Hong Jun Shik, Park Pil Whan, Ahn Jeong Yeal

Abstract excerpt

BACKGROUND: Mutations in calreticulin (CALR) have been reported to be key markers in the molecular diagnosis of myeloid proliferative neoplasms. In most previous reports, CALR mutations were analyzed by using Sanger sequencing. Here, we report a new, rapid, and convenient system for screening CALR mutations without sequencing. METHODS: Eighty-three bone marrow samples were obtained from 81 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27139600
DOI: 10.3343/alm.2016.36.4.291
PMCID: PMC4855047

Genes

CALR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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