Article
Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration.
European journal of oral sciences - 1 Feb 2011
Planello Aline C, Campos Maria I G, Meloto Carolina B, Secolin Rodrigo, Rizatti-Barbosa Célia M, Line Sergio R P, de Souza Ana P
Abstract excerpt
Temporomandibular joint (TMJ) degeneration is a frequent cause of orofacial pain. Matrix metalloproteinases (MMPs) degrade extracellular matrix components and play an important role in TMJ degeneration. We investigated the frequency of the MMP1 1G/2G polymorphism (rs1799750), the MMP3 5A/6A polymorphism (rs3025058), and the MMP9 C/T polymorphism (rs3918242) in individuals with TMJ degeneration, in order to...
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