Article
Enlightening the association between TNF-α -308 G > A and migraine: a meta-analysis with meta-regression and trial sequential analysis.
BMC neurology - 21 Apr 2023
Sudershan Amrit, Sudershan Srishty, Younis Mohd, Bhagat Meenakshi, Pushap Agar Chander, Kumar Hardeep, Kumar Parvinder
Abstract excerpt
BACKGROUND: Migraine is a complex neurological disorder that is characterized by a "lower threshold of neuronal hyperexcitability" with distinctive periodicity and complex vascular dysfunction. Genetic factors have impacted incredibly on the susceptibility of migraine and one such example is the TNF-α 308G > A. AIM: Therefore, we aim to provide a glimpse of the association of the TNF-α 308G > A risk on the...
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