Low-template DNA: A single DNA analysis or two replicates?

doi:10.1016/j.forsciint.2016.04.012

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Article

Low-template DNA: A single DNA analysis or two replicates?

Forensic science international - 1 Jul 2016

Gittelson Simone, Steffen Carolyn R, Coble Michael D

Abstract excerpt

This study investigates the following two questions: (1) Should the DNA analyst concentrate the DNA extract into a single amplification or should he/she split it up to do two replicates? (2) Given the electropherogram obtained from a first analysis, is it worthwhile for the DNA analyst to invest in obtaining a second replicate? A decision-theoretic approach addresses these questions by quantitatively expressing...

Topics

DNA
DNA Fingerprinting
Decision Theory
Genotype
Humans

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PMID: 27131143
DOI: 10.1016/j.forsciint.2016.04.012
PMCID: PMC5225751

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