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Article

Extracellular Cl(-) regulates human SO4 (2-)/anion exchanger SLC26A1 by altering pH sensitivity of anion transport.

Pflugers Archiv : European journal of physiology - 1 Aug 2016

Wu Meng, Heneghan John F, Vandorpe David H, Escobar Laura I, Wu Bai-Lin, Alper Seth L

Abstract excerpt

Genetic deficiency of the SLC26A1 anion exchanger in mice is known to be associated with hyposulfatemia and hyperoxaluria with nephrolithiasis, but many aspects of human SLC26A1 function remain to be explored. We report here the functional characterization of human SLC26A1, a 4,4'-diisothiocyanato-2,2'-stilbenedisulfonic acid (DIDS)-sensitive, electroneutral sodium-independent anion exchanger transporting...

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Identifiers

PMID: 27125215
DOI: 10.1007/s00424-016-1823-8
PMCID: PMC4956541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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