Article

Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange

2023-03-06

Abstract excerpt

Members of the SLC26 family constitute a conserved class of anion transport proteins, which encompasses uncoupled transporters with channel-like properties, coupled exchangers and motor proteins. Among the ten functional paralogs in humans, several participate in the secretion of bicarbonate in exchange with chloride and thus play an important role in maintaining pH homeostasis. Previously, we have elucidated the...

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Literature Corpus work: e6679eca-9068-5196-88d3-ea7141e70289
DOI: 10.1101/2023.03.06.531323

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