Article
Regulated transport of sulfate and oxalate by SLC26A2/DTDST.
American journal of physiology. Cell physiology - 1 Jun 2010
Heneghan John F, Akhavein Arash, Salas Maria J, Shmukler Boris E, Karniski Lawrence P, Vandorpe David H, Alper Seth L
Abstract excerpt
Nephrolithiasis in the Slc26a6(-/-) mouse is accompanied by 50-75% reduction in intestinal oxalate secretion with unchanged intestinal oxalate absorption. The molecular identities of enterocyte pathways for oxalate absorption and for Slc26a6-independent oxalate secretion remain undefined. The reported intestinal expression of SO(4)(2-) transporter SLC26A2 prompted us to characterize transport of oxalate and other...
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