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Article

RpiRc Is a Pleiotropic Effector of Virulence Determinant Synthesis and Attenuates Pathogenicity in Staphylococcus aureus.

Infection and immunity - 1 Jul 2016

Gaupp Rosmarie, Wirf Jessica, Wonnenberg B, Biegel Tanja, Eisenbeis J, Graham J, Herrmann M, Lee C Y, Beisswenger C, Wolz C, Tschernig T, Bischoff M, Somerville G A

Abstract excerpt

In Staphylococcus aureus, metabolism is intimately linked with virulence determinant biosynthesis, and several metabolite-responsive regulators have been reported to mediate this linkage. S. aureus possesses at least three members of the RpiR family of transcriptional regulators. Of the three RpiR homologs, RpiRc is a potential regulator of the pentose phosphate pathway, which also regulates RNAIII levels. RNAIII...

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Identifiers

PMID: 27113358
DOI: 10.1128/IAI.00285-16
PMCID: PMC4936357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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