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RNAIII is linked with the pentose phosphate pathway through the activation of RpiRc in Staphylococcus aureus

9 Apr 2024

Abstract excerpt

ABSTRACT Staphylococcus aureus RNAIII is a dual-function regulatory RNA that controls the expression of multiple virulence genes and especially the transition from adhesion to the production of exotoxins. However, its contribution to S. aureus central metabolism remains unclear. Using MS2-affinity purification coupled with RNA sequencing, we uncovered more than 50 novel RNAIII-mRNA interactions. Among them, we...

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PMID: 38591898
DOI: 10.1128/msphere.00348-23

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