Article
Mutational analysis of HOXA10 gene in Chinese patients with cryptorchidism.
Andrologia - 1 Feb 2017
Cheng Z, Wang M, Xu C, Pei Y, Liu J C, Huang H, He D, Lu P
Abstract excerpt
Cryptorchidism is one of the most common congenital anomalies and affects 2-4% of full-term new born boys. Its aetiology is poorly understood at present. HOXA10 plays a pivotal role in regulation of testicular descent. Male mice mutant for Hoxa10 exhibit unilateral or bilateral cryptorchidism as a result of impaired development of the gubernaculums. In this study, we performed mutation analysis of HOXA10 gene in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.