Article
The variations in the AXIN1 gene and susceptibility to cryptorchidism.
Journal of pediatric urology - 1 Jun 2015
Zhou Bin, Tang Tielong, Chen Peng, Pu Yan, Ma Mingfu, Zhang Danyan, Li Lianbing, Zhang Peng, Song Yaping, Zhang Lin
Abstract excerpt
BACKGROUND: Cryptorchidism is one of the most common congenital anomalies in newborn boys. Although the mechanism responsible for the pathophysiology of cryptorchidism has not yet been well addressed, the Wnt signaling pathway has been involved in the development of cryptorchidism. Axin1 is a central component of the Wnt signaling pathway and may play a critical role in the development of cryptorchidism....
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