Article
Association of PFKM gene polymorphisms and susceptibility to cryptorchidism in a Chinese Han population.
Pediatric surgery international - 1 Sept 2022
Long Siyu, Zhang Ran, Yang Qinni, Wang Yanyun, Song Yaping, Zhou Bin, Zhang Lin
Abstract excerpt
BACKGROUND: Cryptorchidism is one of the most common congenital anomalies in newborn boys. There are various risk factors that have been verified to have relationship with cryptorchidism, including exogenous and genetic, but the pathogenesis of cryptorchidism remains unclear. PFKM gene is a critical gene encodes for a regulatory enzyme, which limits the rate in the pathway of glycolysis. We assumed that...
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