Association of juvenile idiopathic arthritis with PTPN22 rs2476601 is specific to females in a Greek population.

doi:10.1186/s12969-016-0087-3

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Article

Association of juvenile idiopathic arthritis with PTPN22 rs2476601 is specific to females in a Greek population.

Pediatric rheumatology online journal - 23 Apr 2016

Goulielmos G N, Chiaroni-Clarke R C, Dimopoulou D G, Zervou M I, Trachana M, Pratsidou-Gertsi P, Garyfallos A, Ellis J A

Abstract excerpt

BACKGROUND: Juvenile idiopathic arthritis (JIA) is an autoimmune disease characterized by persistent chronic arthritis. Disease risk is believed to be influenced by both genetic and environmental factors. It is well established that the PTPN22 single nucleotide polymorphism (SNP) rs2476601 is associated with JIA susceptibility. It was recently reported in an Australian study that this association is restricted to...

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PMID: 27107590
DOI: 10.1186/s12969-016-0087-3
PMCID: PMC4842296

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PTPN22

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