Article
Targeted Single Gene Mutation in Esophageal Adenocarcinoma.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Lee Katherine T W, Smith Robert A, Gopalan Vinod, Lam Alfred K
Abstract excerpt
Esophageal adenocarcinoma is heterogeneous and studies have reviewed many important mutations that contribute to the pathogenesis of the cancer. These discoveries have helped paved the way into identifying new gene markers or gene targets to develop novel molecular directed therapy for better patient outcomes in esophageal adenocarcinoma. Despite the recent bloom in next-generation sequencing, Sanger sequencing...
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